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Insulin resistance and -cell function in Colombian mestizo and Embera-Chamí populations and their relation with adiposity degree

Caro Gómez, María Antonieta; Naranjo González, Carlos Andrés; Parra Marín, María Victoria; Gallego Lopera, Berta Natalia; Valencia, Diana María; Rúa Molina, Diana Carolina; Rosique Gracia, Javier; García Pineda, Andrés Felipe; Gómez Isaza, Luis Felipe; Pizano Ramírez, Norman Diego; Arcos Palma, Edgar Gerardo; Villegas Perrasse, Alberto del Carmen; Duque Botero, Julieta; Bedoya Berrío, Gabriel de Jesús (ElsevierEspaña, 2017)

Background and objective: Insulin resistance (IR) is a condition favored by metabolic and endocrine changes experienced by adipose tissue in the context of obesity. The prevalence and the presentation of both IR and ...
Perfil lipídico y consumo de frutas y verduras en un grupo de jóvenes de 10 a 19 años, según el índice de masa corporal

Parra Sosa, Beatríz Elena; Manjarrés Correa, Luz Mariela; Velásquez Rodríguez, Claudia María; Agudelo Ochoa, Gloria María; Estrada Restrepo, Alejandro; Uscátegui Peñuela, Rosa Magdalena; Patiño Villada, Fredy Alonso; Bedoya Berrío, Gabriel de Jesús; Parra Marín, María Victoria (Sociedad Colombiana de CardiologíaColombia, 2015)

Introducción: El exceso de peso en ninos ˜ y adolescentes es una pandemia que aumenta el riesgo de mortalidad por enfermedades crónicas no transmisibles. Se ha estimado que aun en etapas tempranas de la vida, el exceso ...
Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population

Orozco Posada, Ana Carolina; Muñoz Contreras, Angélica María; Velásquez Rodríguez, Claudia María; Uscátegui Peñuela, Rosa Magdalena; Patiño Villada, Fredy Alonso; Parra Marín, María Victoria; Manjarrés Correa, Luz Mariela; Parra Sosa, Beatriz Elena; Estrada Restrepo, Alejandro; Agudelo Ochoa, Gloria María (Instituto Nacional de SaludColombia, 2014)

Introduction: Obesity results from interaction between genetic and environmental risk factors. Objective: To evaluate the effect of three gene variants and environmental factors on obesity and overweight in young people ...

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Insulin resistance and -cell function in Colombian mestizo and Embera-Chamí populations and their relation with adiposity degree
...
Caro Gómez, María Antonieta | 2017

Background and objective: Insulin resistance (IR) is a condition favored by metabolic and endocrine changes experienced by adipose tissue in the context of obesity. The prevalence and the presentation of both IR and obesity vary among the populations, and may be affected by ancestral genetic composition among other factors. The aim of this study was to compare the presence of IR and obesity in Amerindians of the Embera-Chamí ethnicity and Colombian mestizo population. Patients and methods: A sample of 630 individuals, 471 mestizos and 159 Amerindians of the Embera-Chamí ethnicity, from the general population of Colombia were studied. For each participant, anthropometric and biochemical measurements, as well as blood pressure and the Homeostatic Model Assessment (HOMA) of IR and -cell function (%B) were recorded. These values were compared between the two populations. Results: While prevalence of central obesity was similar in both populations (48.7% and 42.6% in the mestizo and Embera groups respectively; p = 0.148), body mass index (BMI) values suggested a higher prevalence of overweight in the Embera than in mestizo population (43.4% Embera, 31.8% mestizo; p = 0.027). Despite the similarities in the prevalence of HOMA-IR and HOMA-%B status between both populations, the Embera population had a significantly greater pancreatic ˇ-cell function, higher insulin levels, and better glucose control, across BMI and central obesity categories, than the mestizo population. Conclusion: There are differences in aspects related to energy metabolism between the samples of the mestizo and Amerindian populations analyzed

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Perfil lipídico y consumo de frutas y verduras en un grupo de jóvenes de 10 a 19 años, según el índice de masa corporal
...
Parra Sosa, Beatríz Elena | 2015

Introducción: El exceso de peso en ninos ˜ y adolescentes es una pandemia que aumenta el riesgo de mortalidad por enfermedades crónicas no transmisibles. Se ha estimado que aun en etapas tempranas de la vida, el exceso de peso se asocia con alteraciones metabólicas; sin embargo, es necesario establecer si en nuestro medio estas alteraciones se evidencian en población menor de 19 anos. ˜ Objetivo: Comparar el perfil lipídico y la ingesta de frutas y verduras, según el índice de masa corporal, en un grupo de jóvenes de 10 a 19 anos, ˜ de la empresa promotora de salud SURA, sede de Medellín. Métodos: Estudio de corte transversal, en el que participaron 103 jóvenes obesos, 120 con sobrepeso y 214 con un índice de masa corporal normal. En condiciones basales y ayuno de 10 horas, se evaluó colesterol total, c-LDL, c-HDL y triglicéridos. La ingesta de verduras y frutas se determinó mediante recordatorio de 24 horas. Resultados: Los datos de c-LDL en el grupo de obesos, sobrepeso y control fueron, respectivamente: 95 ± 32, 96 ± 53 y 80 ± 24 mg/dL (p = 0,000); para los mismos grupos, los datos de triglicéridos fueron: 116 ± 65, 112 ± 69 y 88 ± 52 mg/dL (p = 0,000). El c-HDL en los 3 grupos fue: 52 ± 14, 53 ± 12 y 56±14 mg/dL (p = 0,013), respectivamente. Se evidenció una asociación significativa entre el mayor consumo de frutas y la menor concentración de triglicéridos entre los participantes con sobrepeso (p = 0,035). No fue habitual la ingesta de frutas y verduras.Conclusiones: El alto índice de masa corporal promueve un perfil lipídico aterogénico. Son necesarias acciones para promover hábitos alimentarios saludables.

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Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population
...
Orozco Posada, Ana Carolina | 2014

Introduction: Obesity results from interaction between genetic and environmental risk factors. Objective: To evaluate the effect of three gene variants and environmental factors on obesity and overweight in young people aged 10 to 18 years in a Colombian population. Materials and methods: A total of 424 subjects were selected and separated into three groups for a cross-sectional study; 100 obese and 112 overweight subjects were matched with 212 normal-weight controls. Associations were evaluated between excess weight and three genetic polymorphisms (UCP3- rs1800849, FTO-rs17817449, and CAPN10-rs3842570), as well as the family history, the time spent watching television and playing video games, and the diet. Results: A family history of obesity, the time spent watching television and playing video games, the lack of breastfeeding, a low consumption of cereals, legumes, fruits, vegetables, and a high consumption of fast foods were characteristics typically found in obese individuals compared to controls. A significant association between genotype I/I (SNP19 of CAPN10) and excess weight was found even with an active lifestyle. In addition, significant associations between the C/C genotype of the UCP3 gene and the G/G and T/T genotypes of the FTO gene and excess weight were found only in young sedentary individuals. Conclusions: In this population, inadequate diet and sedentary lifestyle increased the risk of excess weight. Genotype I/I of SNP19 in CAPN10 was significantly associated with excess weight. In contrast, FTO and UCP3 variants exhibited effects only in sedentary environments. Key words: Obesity, adolescent, risk factors, motor activity, Colombia

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Listar por tema "Obesidade"

Insulin resistance and -cell function in Colombian mestizo and Embera-Chamí populations and their relation with adiposity degree

Perfil lipídico y consumo de frutas y verduras en un grupo de jóvenes de 10 a 19 años, según el índice de masa corporal

Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population

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Insulin resistance and -cell function in Colombian mestizo and Embera-Chamí populations and their relation with adiposity degree

Perfil lipídico y consumo de frutas y verduras en un grupo de jóvenes de 10 a 19 años, según el índice de masa corporal

Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population

Listar por tema "Obesidade"

Insulin resistance and -cell function in Colombian mestizo and Embera-Chamí populations and their relation with adiposity degree ﻿

Perfil lipídico y consumo de frutas y verduras en un grupo de jóvenes de 10 a 19 años, según el índice de masa corporal ﻿

Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population ﻿

Envíos recientes

Insulin resistance and -cell function in Colombian mestizo and Embera-Chamí populations and their relation with adiposity degree

Perfil lipídico y consumo de frutas y verduras en un grupo de jóvenes de 10 a 19 años, según el índice de masa corporal

Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population

Insulin resistance and -cell function in Colombian mestizo and Embera-Chamí populations and their relation with adiposity degree

Perfil lipídico y consumo de frutas y verduras en un grupo de jóvenes de 10 a 19 años, según el índice de masa corporal

Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population